Emergency crews are responding to an explosion in Northeast Philadelphia after a small medical jet crashed in the area of Roosevelt Boulevard and Cottman Avenue, Philadephia police confirmed to CBS News Philadelphia. 

The medical plane, a Learjet 55, was going from Philadelphia to Springfield, Missouri, leaving the Northeast Philadelphia Airport when tragedy struck. The plane crashed into a neighborhood outside the Roosevelt Mall just moments after leaving the airstrip at around 6:07 p.m. The first call went out to officials at 6:12 p.m.

United States Secretary of Transportation Sean Duffy said there were six people onboard at the time of the crash. According to a statement from Jet Rescue Air Ambulance, the six people were four crew members, a pediatric patient, and the patient's escort. 

A spokesperson for the company said the pediatric patient had just finished treatment in Philadelphia and was being taken back to Mexico. In a previous statement, the company said, "At this time we cannot confirm any survivors."